Most tests read 0.1% of your DNA. We read it all.
Standard tests analyze a few hundred thousand positions on the genome. MyHeritage DNA 360° uses 30x Whole Genome Sequencing to analyze all 3 billion base pairs of your DNA, reading each position 30 times over.
This is what makes in-depth health reports possible.
30× Whole Genome Sequencing
100% of your genome
Other tests
Genotyping arrays
0.1% of your genome
Why choose Whole Genome Sequencing
Most consumer DNA tests use genotyping arrays that only identify variants they’re designed to look for — variants chosen because they’re relatively common. But the variants that can matter most are often the rarest ones, including hereditary disease risks and carrier screening for conditions you could pass on to your children. Whole Genome Sequencing reads the underlying DNA, so it can identify the rare variants that standard arrays were never designed to find.
The MyHeritage DNA 360° difference
MyHeritage DNA 360° is built for accuracy in the parts of the genome that are hardest to read.
Measured, not predicted
Genotyping arrays and low-pass sequencing use imputation, a statistical method that reconstructs parts of the genome from large population datasets. It's the standard for genetic genealogy, but rare variants are much harder for such methods to reconstruct. At 30x coverage, your health reports are based on your DNA as it was actually read.
Newer, more reliable chemistry
When we amplify DNA, we use Solaris 2.0 chemistry, chosen for how reliably it handles repetitive letters, instead of older methods that are more prone to miscounts.
30 independent reads of each position
Each position on your genome is read 30 times on average, ensuring that no single misread could determine a result.
Each fragment is read from both ends
Reading each DNA fragment from both ends gives us two anchor points instead of one, which makes it far clearer where the fragment belongs — especially in repetitive stretches, where a single read could fit in many places.
How It Works
Order Online
MyHeritage DNA 360°
kit arrives to your home
Collect & Return
A 2-minute cheek swab, then mail it back to our lab for sample analysis
Results Are Ready
Access detailed, easy-to-understand reports online
Where your sample is analyzed
All DNA samples are processed at the Gene by Gene laboratory in Houston, Texas using sequencing instruments from Ultima Genomics.
Gene by Gene is a CLIA-certified, CAP-accredited lab that has been MyHeritage’s trusted partner and laboratory of choice since the MyHeritage DNA test was first launched in 2016.
Every sample is analyzed to the same standards required of clinical diagnostic laboratories in the United States, and undergoes a rigorous quality control process to ensure the integrity of the data.
From raw data to report
Whole Genome Sequencing produces an enormous amount of data. Turning it into a useful report means finding where your DNA differs from the reference genome, and then explaining what those differences mean for you.
Your variants are identified
Your full genome is compared against the human reference genome to find the positions where yours differs. These differences are called variants, and most of them are harmless.
Classified to clinical genetics standards
Variants in your health reports are classified using the standards of the American College of Medical Genetics and Genomics (ACMG), the same five-tier framework used in clinical genetics, ranked from pathogenic to benign. A variant is reported as significant only when the published evidence supports it. Every variant included in your reports has been selected and curated by geneticists.
Written to be understood
Your reports clearly explain which genetic variants were found, what's known about them, and what they do and don’t tell you about your health. You don’t need a scientific background to make sense of them.
New insights added over time
Genetic research is constantly advancing. Because your whole genome has already been sequenced, new findings can be drawn from the same data, without taking another DNA test.
The only DNA test you need
MyHeritage DNA 360° uses 30x Whole Genome Sequencing to provide clear, actionable insights into your health, wellness, genetic origins, and more.
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The MyHeritage DNA 360° test is for informational purposes only. It is not a diagnostic test and is not a substitute for professional medical advice. Always consult a qualified healthcare provider with any questions about your health.